Four female medical graduates of Al-Quds University in Jerusalem have conducted research on a rare genetic disease and published their findings in the European Journal of Case Reports in Internal Medicine, the official journal of the European Federation of Internal Medicine, on December 4, 2025. Their research on the rare Vascular Ehlers-Danlos Syndrome, one of the most severe heritable connective tissue disorders, analyzed three clinical cases, highlighting challenges of early diagnosis and difficulties in medical intervention.1 Through the case studies, they examined ways to reduce “catastrophic complications” and improve treatment and follow-up. They found that long-term surveillance is critical, but even with it, “outcomes remain poor.”2 They conclude: “These cases underscore both the progress made and the unmet need for novel therapeutic options to improve outcomes in this high-risk population.”3
The four authors are Tala Sulaiman, Adriana Skafi, Razan Fiala, and Lara Alayasa.
